Rosenberg Research Paper

Rosenberg Research Paper-67
I was struck by her determination to leave no stone unturned.It was remarkable to me that she, almost serendipitously, discovered the opportunity to participate in this trial through her participation in Project LEAD a year or two earlier.

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Give an important caution BUT quickly trump it with a grandiose claim that is not supported by current evidence; a glowing, eye-catching, optimistic, and hopeful promise — as variously described in this single Guardian article : It’s interesting that the aforementioned Guardian article, despite its parade of hyped language, did balance the story with some of these cautions. Oncologists have long been aware of a lucky few — dubbed “Exceptional or Super Responders” — who respond to a therapy that over 90% of other patients do not respond to.

As mentioned in this 2015 research paper by oncologists Vinay Prasad and Andrae Vandross, it’s very hard to know if the exceptional response is because of the treatment given or because of some biological characteristic unique to the responder’s tumor.

The prospect of harnessing our own immune system to attack cancer cells is a compelling and worthwhile avenue of research.

But as it stands now there’s insufficient evidence to make statements regarding efficacy, safety, costs, or how these treatments stack up against existing therapies.

I think this (her story) is an important lesson about advocacy and, in particular, self-advocacy.

After every other chemotherapy protocol failed, she was adrift.

Jonathan La Pook, a chief medical correspondent at CBS: It’s an anecdote.

But that doesn’t stop La Pook — a physician — from calling this See the trend? Also, there is another caution that rarely makes its way to the general public.

A 49-year-old Floridian named Judy Perkins with metastatic breast cancer, whose illness has progressed despite multiple trials of chemotherapy, goes into complete remission after being treated with immunotherapy by Steven Rosenberg, MD, Ph D — whom CBS dubs “a pioneer in harnessing the immune system to fight cancer.” Rosenberg is no stranger to the spotlight.

He became a media darling in 1985 when his research on interleukin-2 generated mega-coverage best described as long on hype but short on scrutiny.


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