Assigning R And S Configuration

There are no wedges indicating which direction the group is pointing, so we can't assign stereochemistry at this center.

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Take a peek at the two organic molecules below; they are mirror images, but if you tried to lay them on top of each other, the groups would never line up perfectly.

This is what is meant by 'non-superimposable.' This is a tough concept, so let's consider a real life example. Now, try to put one hand on top of the other with the palms facing down. In fact, 19 out of 20 of the amino acids that make up your body are chiral!

You learned how to determine if the absolute stereochemistry is R or S, and how to deal with situations where the lowest priority group is not pointing away from you.

Finally, you saw how to assign absolute configuration in cyclic molecules. We have over 200 college courses that prepare you to earn credit by exam that is accepted by over 1,500 colleges and universities.

If a molecule has one stereocenter of R configuration, then in the mirror image of that molecule, the stereocenter would be of S configuration, and vice-versa.

Determination of R or S configuration can be applied in three steps: 1.

If the molecule has just one chiral carbon, these two configurations are called enantiomers.

The two possible molecules are mirror images of each other, but they are non-superimposable.

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